Policy Tracker · Psilocybin · United States
Is psilocybin legal in Oklahoma?
No — psilocybin is illegal in Oklahoma.
Recorded status
Prohibited
In effect since 2026-05-12
Psilocybin and psilocyn are Schedule I hallucinogenic substances under 63 O.S. § 2-204. Oklahoma has no psilocybin therapy or decriminalization law; House-passed psilocybin research bills, including HB 2107 (2023), did not become law, and the 2026 Breakthrough Therapy Act (HB 3834) covers ibogaine only.
Psilocybin remains a Schedule I substance under US federal law regardless of state rules.
Source
Oklahoma Statutes Title 63 (§ 2-204, Schedule I) · oksenate.gov
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