Policy Tracker · Psilocybin · United States
Is psilocybin legal in South Dakota?
No — psilocybin is illegal in South Dakota.
Recorded status
Prohibited
In effect since 2026-03-10
Signed into law: HB1099 — Reschedule the pharmaceutical composition of crystalline polymorph psilocybin in a drug product approved by the Food and Drug Administration as a Schedule IV controlled substance. (Scheduling, Mar 10, 2026).
Psilocybin remains a Schedule I substance under US federal law regardless of state rules.
Source
PoliPsy legislation tracker · polipsy.dev
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